Suk-Heung Oh , Jin-Ju Yu, Hae-Jin Kim, Ki-Wan Oh, Jae-Soon Eun
Abstract
This study was conducted to investigate whether the white lotus extracts could enhance the pentobarbital-induced sleeping behaviors and chloride influx, as well as have an antioxidant function. When accessing the effect on sleeping behaviors, extract from the dried mature leaf (DML) increased sleeping time more than twice compared with the control group. Also, the DML extract increased chloride influx in primary cultured cerebellar granule cells. The antioxidant function of white lotus extracts derived from young leaf, DML, and ovary had similar performance when being compared to ascorbic acid. The result suggested that white lotus extracts could contain components that are able to potentiate pentobarbital-induced sleep behaviors and to activate chloride channel, as well as antioxidant function.
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Keywords
white lotus, sleeping, chloride influx, antioxidant
